DESIGN TOOLS
company

跟随我们的直觉:支持两家开拓性的医疗保健初创公司

Gayathri (G) Radhakrishnan | August 2021

When it comes to healthcare investments, the Micron Ventures team is just getting started. Our team is always on the hunt to find startups who are truly innovative in their application of AI and Machine Learning (ML) across various problem domains. 我们被医疗保健领域的无限可能性所吸引 & life sciences.

我们的使命很简单:释放科技领域最具创新性的初创企业. 投资医疗保健是美光的新关注点, and many entrepreneurs ask us, “为什么一家半导体公司想要投资我们?“作为推动一些最大数据转换的技术领导者, 在美光,我们相信通过人工智能进行真正的创新——而且我们很有眼光, 但坚定地支持具有改变潜力的突破性工作, or even save lives.

Recently, we announced our investment in two healthcare startups focused on innovations in gastrointestinal health. DayTwo leverages microbiome data combined with AI to manage chronic metabolic conditions (like diabetes, pre-diabetes, 和临床肥胖)通过食物而不是昂贵的药物. 迭代范围带来尖端的精确医学胃肠病学, 改变内窥镜视频分析的游戏规则, which in its current state is known for being subjective; a costly matter when making decisions about health.

1 in 3 Americans have pre-diabetes

你没看错:美国有8800万成年人处于糖尿病前期. 3400万美国人患有糖尿病.5% of the US population. The costs are not cheap: 1 in every 7 health care dollars is spent on diabetes and its complications1. 该领域的许多公司都在寻求解决代谢性疾病, but most methods employ a mix of pharmaceuticals while also requiring people to adhere to diets that eliminate or strictly limit intake of carbohydrates. 这通常意味着彻底改变饮食习惯. What happens then? 人们很难遵守给他们的指导. Habits are hard to break.

What if food is the answer?

想象一下,如果我们不被要求放弃我们喜欢的食物,会有什么样的可能性, but rather learned how to add foods that would help us achieve the glycemic balance we need? DayTwo is applying AI to microbiome data and a combination of other biomarkers to help people manage diabetes through food instead of expensive pharmaceuticals. Microbiome sampling and analysis is a hot topic in medicine; researchers are studying the benefits of how such samples can inform health diagnosis and care. 微生物群极其复杂,由超过100万亿个生物体组成. Analysis of a person’s gut flora could take lifetimes; but the combination of advanced computing hardware combined with AI has reduced this task to minutes.

DayTwo的科学证明了食物就是药物. The program enables people to make small tweaks to their existing meals in order to keep blood sugar in the healthy range. 人们对同样的食物反应不同. 假设你和你最好的朋友每天早上一起吃早餐. It’s a ritual and it brings you joy. 你吃同样的菜,但你的个人血糖水平会有所不同. 也许你的血糖会飙升,而你朋友的不会. 而不是建议你把最喜欢的食物从你的饮食中完全剔除, DayTwo可以建议做一些小调整,比如在酸奶中加入核桃, or butter to rice, 这将中和你的血糖峰值——所有这些都是基于你独特的微生物群.

Why did Micron invest?

DayTwo is the only known microbiome based solution that has demonstrated sustainable outcomes in both clinical and real world settings. And that’s just the beginning. 肠道微生物群影响着许多健康状况,比如糖尿病, pre-diabetes, 肥胖和其他疾病. Advancements are so rich that in the near future when you go for a routine wellness checkup, 他们可能会收集你的微生物群样本以及血液和尿液.

来预测血糖对任何食物的反应, scientists need a high-resolution view of the microbiome and a dataset large enough to make accurate predictions. DayTwo holds the world's largest and richest proprietary gut microbiome dataset and has tremendous opportunities to apply its science and IP to improve outcomes for other diseases. 美国国立卫生研究院(NIH)的“我们所有人”倡议旨在收集数据, including microbiome samples, 从100多万人身上受益的精准医疗. NIH recently cited DayTwo’s science as a foundation for its precision nutrition research. 欲了解更多有关DayTwo创新微生物组解决方案的信息,请访问他们的网站 website.

检测美国第二大致命癌症是非常主观的

结肠癌是美国癌症死亡的第二大常见原因2. 预计将增加60%,达到2人以上.2 million new cases and 1.1 million cancer deaths by 20303. 内窥镜检查是筛查结直肠癌的金标准, 但在筛查过程中,20%的息肉被遗漏了4. Current endoscopic procedures are based largely on clinical intuition and produce highly subjective results, 导致在解释上的巨大差异. 内窥镜检查是主观的,有许多类型的异常息肉, 它们非常小,很容易被人眼忽略. 如果临床医生在做手术时遗漏了什么, there’s no way to go back and find it.

Inflammatory Bowel Disease (IBD) is an umbrella term to indicate chronic inflammation of your digestive tract and includes Crohn’s disease and Ulcerative Colitis, 总共影响了大约300万美国人. The severity of the condition is measured using a scoring technique called Mayo Endoscopic Score (MES). The physician who performs the endoscopy or the one reviewing the recorded endoscopy video may rate disease activity using this scoring index. 它是在1987年开发的,用于评估最初的疾病严重程度, change in activity over time, and response to treatment. Unfortunately, this scoring technique is highly subjective and does not truly capture the pain experienced by the patient.

用直觉交换数据支持的洞察力

在肿瘤学和传染病方面取得了显著进展, why not gastroenterology? 迭代范围开发了一种息肉检测算法, SKOUT, 这有助于临床医生识别难以看到的息肉, 提高决策的准确性. SKOUT puts a bounding box around polyps to bring it to the clinician’s attention live during the procedure. 将这项技术称为肠道GPS未免过于简单化了, 但如果你曾经在路上对自己想过, “如果没有GPS,我永远也找不到这个,“这种类比确实有道理.

When it comes to IBD, it’s so subjective to score the severity that there are many missed opportunities for clinical trial candidates. It is difficult to monitor the efficacy of various treatments since it’s a syndrome — not just one set of symptoms, 所以临床试验选择和治疗分析都是非常主观的. Iterative Scopes has automated the interpretation of colonoscopy videos and can assist both in patient selection for clinical trials and for understanding pharmaceutical efficacy.

ventures-blog-secondaryimage.一群“倡议范围”的人在他们的办公室前
沙巴体育安卓版下载迭代作用域的信息,请访问他们的 website.

\r\n

At the end of the day, the gut is one of the last truly uncharted territories in the human body. 随着DayTwo和Iterative Scopes等公司的进步, we look forward to potential future advancements that uncover the depths of the gut–brain axis, 身体中最强大的关系之一.

\r\n

如果你是一家利用人工智能进行创新的科技创业公司, check out our Micron Ventures page to see what we’re looking for — and don’t be shy about reaching out to us!

\r\n

1 Cost of Diabetes

\r\n

2 结肠癌是癌症相关死亡的第二大原因

\r\n

3 结直肠癌发病率和死亡率的全球模式和趋势- PubMed.gov)

\r\n

4 连续结肠镜检查结直肠肿瘤息肉的漏检率

\r\n"}}' id="text-ff391d225b">

迭代范围团队在上面的图片

Why did Micron invest?

Colonoscopy videos are not usually recorded or stored; however, Iterative Scopes has scaled data acquisition to yield the largest collection of such annotated data. This matters because ML technologies depend heavily on solid training data to achieve a higher level of accuracy. Iterative Scopes focuses on both Colorectal Cancer and IBD and has potential to impact a large population. Gastroenterology has not seen as much innovation as other disciplines have leveraging machine learning to enable precision medicine. Iterative Scopes has the strength of the team and advisory board combined with pharma partners such as Eli Lilly and JJDC, because of this, we believe that they have the combined technology and brain trust to drive a meaningful impact in the world of gastroenterology. 要了解更多沙巴体育安卓版下载迭代作用域的信息,请访问他们的 website.

At the end of the day, the gut is one of the last truly uncharted territories in the human body. 随着DayTwo和Iterative Scopes等公司的进步, we look forward to potential future advancements that uncover the depths of the gut–brain axis, 身体中最强大的关系之一.

如果你是一家利用人工智能进行创新的科技创业公司, check out our Micron Ventures page to see what we’re looking for — and don’t be shy about reaching out to us!

1 Cost of Diabetes

2 结肠癌是癌症相关死亡的第二大原因

3 结直肠癌发病率和死亡率的全球模式和趋势- PubMed.gov)

4 连续结肠镜检查结直肠肿瘤息肉的漏检率

Senior Director, Corporate Development

Gayathri Radhakrishnan

G来自美光创投(Micron Ventures),来自我们的人工智能基金. 她投资于利用人工智能和机器学习解决制造业关键问题的初创公司, health care, automotive and beyond. 她在沙巴体育结算平台管理方面拥有20年的多学科经验, product marketing, corporate strategy, M&A and venture investments.